Cytotoxicity: IC 50 retinol 25μM, retinol retinoic acid ester is 40μM (60% higher than retinol), retinoic acid is a prescription drug, and it is forbidden to be used in personal care (IC 50 is a certain concentration of certain substance to induce 50% of the amount of cell apoptosis, used to measure the ability of the substance to induce apoptosis. The higher the cell toxicity, the weaker);
Biological activity: Retinol retinoate retains the cyclic end groups and side chain alkenyl groups, and still has the biological activity of retinol and retinoic acid. In vivo tests show that the ability to promote skin regeneration is better than that of retinol and retinoic acid. ; Improve the optical stability and chemical stability of retinol, while reducing the irritation of retinol and retinoic acid.
Applications of Cosmetic Grade Skin Anti-aging Ingredient Vitamin A Derivative Retinyl Retinoate:
Anti-aging products: Maintain the collagen in the dermis and prevent the collagen from degrading too fast. Compounded with hyaluronic acid and bio-complex polysaccharide (hydrolyzed myrtle), the improvement of fine lines can be observed within a week.
Whitening products: Cooperate with VC to inhibit tyrosinase, promote metabolism, and accelerate the disappearance of melanin. The literature shows that it is equally effective in treating acne skin when combined with VC.
Sunscreen products: Inhibit the enhancement of MMP activity caused by ultraviolet rays, protect elastin and dermal collagen, and improve wrinkles and fine lines caused by UV irradiation.
Repair products: promote the synthesis of hyaluronic acid in the body, reduce the TEWL of the skin, promote the activity of keratinocytes, increase the thickness of the epidermis, and make the epidermis stronger.